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1

Glycine supplementation extends lifespan of male and female mice

Miller, Richard A., Harrison, David E., Astle, C. Michael, Bogue, Molly A., Brind, Joel, Fernandez, Elizabeth, Flurkey, Kevin, Javors, Martin, Ladiges, Warren, Leeuwenburgh, Christiaan, Macchiarini, F

Journal:

Year:

2019

Language:

english

File:

PDF, 678 KB

english, 2019

2

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

Harrison, David E., Strong, Randy, Sharp, Zelton Dave, Nelson, James F., Astle, Clinton M., Flurkey, Kevin, Nadon, Nancy L., Wilkinson, J. Erby, Frenkel, Krystyna, Carter, Christy S., Pahor, Marco, Ja

Journal:

Year:

2009

Language:

english

File:

PDF, 447 KB

english, 2009

3

Orthogonal projection to latent structures solution properties for chemometrics and systems biology data

David J. Biagioni, David P. Astling, Peter Graf, Mark F. Davis

Journal:

Journal of Chemometrics

Year:

2011

Language:

english

File:

PDF, 1.00 MB

english, 2011

4

Evaluation of matrix effects in analysis of estrogen using liquid chromatography–tandem mass spectrometry

Hien P. Nguyen, Li Li, Imam S. Nethrapalli, Ningning Guo, C. Dominique Toran-Allerand, David E. Harrison, C. Michael Astle, Kevin A. Schug

Journal:

Journal of Separation Science

Year:

2011

Language:

english

File:

PDF, 186 KB

english, 2011

5

Preparation of methyl 3,6-dideoxy-α-d-xylo-hexopyranoside (methyl α-abequoside) and its α-l-lyxo isomer by reduction of epoxides with lithium triethylborohydride

Hans H. Baer, David J. Astles

Journal:

Carbohydrate Research

Year:

1984

Language:

english

File:

PDF, 329 KB

english, 1984

6

Tandem thermal Claisen?Cope rearrangements of coumarate derivatives. Total syntheses of the naturally occurring coumarins: suberosin, demethylsuberosin, ostruthin, balsamiferone and gravelliferone

Cairns, Nicholas, Harwood, Laurence M., Astles, David P.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1994

Language:

english

File:

PDF, 1.03 MB

english, 1994

7

Population Structure and Cryptic Relatedness in Genetic Association Studies

William Astle and David J. Balding

Journal:

Statistical Science

Year:

2009

Language:

english

File:

PDF, 3.21 MB

english, 2009

8

Future Artificial Pancreas Technology for Type 1 Diabetes: What Do Users Want?

Barnard, Katharine D., Pinsker, Jordan E., Oliver, Nick, Astle, Annabel, Dassau, Eyal, Kerr, David

Journal:

Diabetes Technology & Therapeutics

Year:

2015

Language:

english

File:

PDF, 135 KB

english, 2015

9

Modified nucleotides may have enhanced early RNA catalysis

Wolk, Steven K., Mayfield, Wesley S., Gelinas, Amy D., Astling, David, Guillot, Jessica, Brody, Edward N., Janjic, Nebojsa, Gold, Larry

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

Language:

english

File:

PDF, 801 KB

english, 2020

10

Chemical synthesis of 3-amino-2,3-dideoxy-d-myo-inositol (an intermediate in the biosynthesis of 2-deoxystreptamine) and its d-epi stereoisomer

Hans H. Baer, Lisa Siemsen, David J. Astles

Journal:

Carbohydrate Research

Year:

1986

Language:

english

File:

PDF, 597 KB

english, 1986

11

Syntheses of 6-acylcoumarins via highly regioselective fries rearrangements. Total syntheses of the linear acylated coumarins geijerin and dehydrogeijerin.

Nicholas Cairns, Laurence M. Harwood, David P. Astles

Journal:

Year:

1992

Language:

english

File:

PDF, 1.03 MB

english, 1992

12

Efficient, highly regioselective fries rearrangements of methyl 3-(2-acyloxy-4-methoxyphenyl)propanoates: The first total syntheses of the linear acylated coumarins geijerin and dehydrogeijerin.

Nicholas Cairns, Laurence M. Harwood, David P.pp]Astles

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 233 KB

english, 1988

13

InGaN/GaN LEDs grown on Si(111): dependence of device performance on threading dislocation density and emission wavelength

Dandan Zhu, Clifford McAleese, Maik Häberlen, Carmen Salcianu, Ted Thrush, Menno Kappers, Andrew Phillips, Penelope Lane, Michael Kane, David Wallis, Trevor Martin, Mike Astles, Colin Humphreys

Journal:

physica status solidi (c)

Year:

2010

Language:

english

File:

PDF, 194 KB

english, 2010

14

Assessing permanent damage to primitive hematopoietic stem cells after chemotherapy using the competitive repopulation assay

Renee V. Gardner, Charles Lerner, Clinton M. Astle, David E. Harrison

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 647 KB

english, 1993

15

Differential effects of chemoreceptor methylation-domain mutations on swarming and development in the social bacterium Myxococcus xanthus

David P. Astling, Josephine Y. Lee, David R. Zusman

Journal:

Molecular Microbiology

Year:

2006

Language:

english

File:

PDF, 399 KB

english, 2006

16

An aging Interventions Testing Program: study design and interim report

Richard A. Miller, David E. Harrison, Clinton M. Astle, Robert A. Floyd, Kevin Flurkey, Kenneth L. Hensley, Martin A. Javors, Christiaan Leeuwenburgh, James F. Nelson, Ennio Ongini, Nancy L. Nadon, Hu

Journal:

Year:

2007

Language:

english

File:

PDF, 342 KB

english, 2007

17

Genetic regulation of hematopoietic stem cell exhaustion during development and growth

Rong Yuan, C.M. Astle, Jichun Chen, David E. Harrison

Journal:

Experimental Hematology

Year:

2005

Language:

english

File:

PDF, 317 KB

english, 2005

18

Mice severely deficient in growth hormone have normal hematopoiesis

Yashoda Sharma, Kevin Flurkey, C. Michael Astle, David E. Harrison

Journal:

Experimental Hematology

Year:

2005

Language:

english

File:

PDF, 332 KB

english, 2005

19

Heterozygous Kit Mutants with Little or No Apparent Anemia Exhibit Large Defects in Overall Hematopoietic Stem Cell Function

Yashoda Sharma, Clinton M. Astle, David E. Harrison

Journal:

Experimental Hematology

Year:

2007

Language:

english

File:

PDF, 695 KB

english, 2007

20

Characterization of a hematopoietic stem cell with engraftment advantage

Jichun Chen, Clinton M. Astle, David E. Harrison

Journal:

Experimental Hematology

Year:

2000

Language:

english

File:

PDF, 14 KB

english, 2000

21

Hematopoietic senescence is postponed and hematopoietic stem cell function is enhanced by dietary restriction

Jichun Chen, Clinton M Astle, David E Harrison

Journal:

Experimental Hematology

Year:

2003

Language:

english

File:

PDF, 247 KB

english, 2003

22

Development and aging of primitive hematopoietic stem cells in BALB/cBy mice

Jichun Chen, Clinton M Astle, David E Harrison

Journal:

Experimental Hematology

Year:

1999

Language:

english

File:

PDF, 262 KB

english, 1999

23

Genetic regulation of primitive hematopoietic stem cell senescence

Jichun Chen, Clinton M Astle, David E Harrison

Journal:

Experimental Hematology

Year:

2000

Language:

english

File:

PDF, 96 KB

english, 2000

24

Mitogen synergism in low-responding CBA/CaJ mice

Clinton M. Astle, David E. Harrison

Journal:

Cellular Immunology

Year:

1976

Language:

english

File:

PDF, 323 KB

english, 1976

25

Thyroid surgery in children and adolescents

Jaromír Astl, Marcela Dvořáková, Petr Vlček, David Veselý, Petr Matucha, Jan Betka

Journal:

International Journal of Pediatric Otorhinolaryngology

Year:

2004

Language:

english

File:

PDF, 103 KB

english, 2004

26

Telemedicine approach to screening for severe retinopathy of prematurity: a pilot study

Anna L Ells, Jonathan M Holmes, William F Astle, Geoff Williams, David A Leske, Michael Fielden, Brad Uphill, Penny Jennett, Marilynne Hebert

Journal:

Year:

2003

Language:

english

File:

PDF, 102 KB

english, 2003

27

Myocardial ischemia correlates with reduced fibrinolytic activity following peripheral vascular surgery

David A Lubarsky, Stacy D Fisher, Thomas F Slaughter, Cynthia L Green, Catherine K Lineberger, J.Rex Astles, Charles S Greenberg, W.Warriner Inge III, Mitchell W Krucoff

Journal:

Journal of Clinical Anesthesia

Year:

2000

Language:

english

File:

PDF, 163 KB

english, 2000

28

Mutations in CYP1B1, the Gene for Cytochrome P4501B1, Are the Predominant Cause of Primary Congenital Glaucoma in Saudi Arabia

Bassem A. Bejjani, Richard Alan Lewis, Karim F. Tomey, Kent L. Anderson, David K. Dueker, Monzer Jabak, William F. Astle, Brith Otterud, Mark Leppert, James R. Lupski

Journal:

The American Journal of Human Genetics

Year:

1998

Language:

english

File:

PDF, 1.57 MB

english, 1998

29

Acyl-CoA:Cholesterol O -Acyltransferase (ACAT) Inhibitors. 2. 2-(1,3-Dioxan-2-yl)-4,5-diphenyl-1 H -imidazoles as Potent Inhibitors of ACAT

Astles, Peter C., Ashton, Michael J., Bridge, Andrew W., Harris, Neil V., Hart, Terrance W., Parrott, David P., Porter, Barry, Riddell, David, Smith, Christopher, Williams, Robert J.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 568 KB

english, 1996

30

Partition coefficients of tetrachlorobenzene isomers between water and sodium dodecylsulfate micelles: relation to toxicity

David J. Astles, Robert Pearce, David Griller, Harold M. Schwartz, David C. Villeneuve

Journal:

Year:

1987

Language:

english

File:

PDF, 268 KB

english, 1987

31

CARDIAC-ARIA: Measuring the Accessibility to Cardiovascular Services in Rural and Remote Australia Via Applied Geographical Spatial Technology (GIS)

Robyn Clark, Andrew Tonkin, David Wilkinson, Kerena Eckert, Neil Coffee, Peter Astles, Marianne Milligan, Simon Stewart

Journal:

Heart Lung & Circulation

Year:

2008

Language:

english

File:

PDF, 77 KB

english, 2008

32

Efficiency measurement of GaN-based quantum well and light-emitting diode structures grown on silicon substrates

Zhu, Dandan, McAleese, Clifford, HaÌberlen, Maik, Salcianu, Carmen, Thrush, Ted, Kappers, Menno, Phillips, Andrew, Lane, Penelope, Kane, Michael, Wallis, David, Martin, Trevor, Astles, Mike, Hylton,

Journal:

Journal of Applied Physics

Year:

2011

Language:

english

File:

PDF, 1.07 MB

english, 2011

33

A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins

Keysar, Stephen B., Astling, David P., Anderson, Ryan T., Vogler, Brian W., Bowles, Daniel W., Morton, J. Jason, Paylor, Jeramiah J., Glogowska, Magdalena J., Le, Phuong N., Eagles-Soukup, Justin R.,

Journal:

Molecular Oncology

Year:

2013

Language:

english

File:

PDF, 3.29 MB

english, 2013

34

[Part 1: Biological Sciences] || Effects of Food Restriction on Aging: Separation of Food Intake and Adiposity

David E. Harrison, Jonathan R. Archer and Clinton M. Astle

Journal:

Proceedings of the National Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 861 KB

english, 1984

35

Number and Continuous Proliferative Pattern of Transplanted Primitive Immunohematopoietic Stem Cells

David E. Harrison, Clinton M. Astle and Charles Lerner

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 793 KB

english, 1988

36

Finished sequence and assembly of the DUF1220-rich 1q21 region using a haploid human genome

O¿Bleness, Majesta, Searles, Veronica B, Dickens, C Michael, Astling, David, Albracht, Derek, Mak, Angel C, Lai, Yvonne Y, Lin, Chin, Chu, Catherine, Graves, Tina, Kwok, Pui-Yan, Wilson, Richard K, Si

Journal:

Year:

2014

Language:

english

File:

PDF, 1.70 MB

english, 2014

37

A Bayesian Model of NMR Spectra for the Deconvolution and Quantification of Metabolites in Complex Biological Mixtures

Astle, William, De Iorio, Maria, Richardson, Sylvia, Stephens, David, Ebbels, Timothy

Journal:

Journal of the American Statistical Association

Year:

2012

Language:

english

File:

PDF, 872 KB

english, 2012

38

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

Harrison, David E., Strong, Randy, Allison, David B., Ames, Bruce N., Astle, Clinton M., Atamna, Hani, Fernandez, Elizabeth, Flurkey, Kevin, Javors, Martin A., Nadon, Nancy L., Nelson, James F., Pletc

Journal:

Year:

2014

Language:

english

File:

PDF, 1.03 MB

english, 2014

39

Aminopyrazolones: novel photosystem II inhibitors

Camilleri, Patrick, Astles, David P., Kerr, Michael W., Spencer, John E.

Journal:

Journal of Agricultural and Food Chemistry

Year:

1990

Language:

english

File:

PDF, 271 KB

english, 1990

40

An iterative procedure for the synthesis of the diprenylated coumarins balsamiferone and gravelliferone from umbelliferone via multiple [3.3] sigmatropic rearrangements

Cairns, Nicholas, Harwood, Laurence M., Astles, David P.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1987

Language:

english

File:

PDF, 200 KB

english, 1987

41

Boron halide catalysed regioselective ortho-Claisen rearrangements of 4?-allyloxycoumaric acid derivatives: total synthesis of demethylsuberosin

Cairns, Nicholas, Harwood, Laurence M., Astles, David P., Orr, Alex

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1994

Language:

english

File:

PDF, 923 KB

english, 1994

42

Application of the Lewis acid-catalysed Claisen rearrangement of 4?-(1,1-dimethylallyloxy) coumarates to the synthesis of demethylsuberosin

Cairns, Nicholas, Harwood, Laurence M., Astles, David P.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1986

Language:

english

File:

PDF, 216 KB

english, 1986

43

Regioselective preparation of 6-allyl-7-hydroxycoumarin from 7-allyloxycoumarin via boron halide catalysed ortho-Claisen rearrangement of 4?-allyloxycoumaric acid derivatives

Cairns, Nicholas, Harwood, Laurence M., Astles, David P., Orr, Alex

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1986

Language:

english

File:

PDF, 203 KB

english, 1986

44

Synthesis of linear coumarins via para-Claisen rearrangement of coumarate ester derivatives: total synthesis of suberosin, demethylsuberosin, and ostruthin

Cairns, Nicholas, Harwood, Laurence M., Astles, David P.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1986

Language:

english

File:

PDF, 211 KB

english, 1986

45

The formation of branched-chain deoxypentofuranosides by ring contraction in the reductive desulfonyloxylation of hexopyranoside p -toluenesulfonates

Baer, Hans H., Astles, David J., Chin, Ho-Chi, Siemsen, Lisa

Journal:

Canadian Journal of Chemistry

Year:

1985

Language:

english

File:

PDF, 640 KB

english, 1985

46

Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

Miller, Richard A., Harrison, David E., Astle, Clinton M., Fernandez, Elizabeth, Flurkey, Kevin, Han, Melissa, Javors, Martin A., Li, Xinna, Nadon, Nancy L., Nelson, James F., Pletcher, Scott, Salmon,

Journal:

Year:

2014

Language:

english

File:

PDF, 507 KB

english, 2014

47

Regulation of Selenoproteins and Methionine Sulfoxide Reductases A and B1 by Age, Calorie Restriction, and Dietary Selenium in Mice

Novoselov, Sergey V., Kim, Hwa-Young, Hua, Deame, Lee, Byung Cheon, Astle, Clinton M., Harrison, David E., Friguet, Bertrand, Moustafa, Mohamed E., Carlson, Bradley A., Hatfield, Dolph L., Gladyshev,

Journal:

Antioxidants & Redox Signaling

Year:

2010

Language:

english

File:

PDF, 8.01 MB

english, 2010

48

Genetically diverse mice are novel and valuable models of age-associated susceptibility toMycobacterium tuberculosis

Harrison, David E, Astle, Clinton M, Niazi, M, Major, Samuel, Beamer, Gillian L

Journal:

Immunity & Ageing

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

49

Respiratory outcomes study (RESPOS) for preterm infants at primary school age

Astle, Valerie, Broom, Margaret, Todd, David A., Charles, Blessy, Ringland, Cathy, Ciszek, Karen, Shadbolt, Bruce

Journal:

Journal of Asthma

Year:

2015

Language:

english

File:

PDF, 150 KB

english, 2015

50

Postoperative Glaucoma Following Infantile Cataract Surgery

Mataftsi, Asimina, Haidich, Anna-Bettina, Kokkali, Stamatia, Rabiah, Peter K., Birch, Eileen, Stager, David R., Cheong-Leen, Richard, Singh, Vineet, Egbert, James E., Astle, William F., Lambert, Scott

Journal:

JAMA Ophthalmology

Year:

2014

Language:

english

File:

PDF, 456 KB

english, 2014